A Randomized Controlled Trial to Assess the Effect of Lidocaine Administered via Throat Spray and Nebulization in Patients with Refractory Chronic Cough

Author(s) Abdulqawi R.; Satia I.; Kanemitsu Y.; Khalid S.; Holt K. et al.
Source The journal of allergy and clinical immunology. In practice; Nov 2020
Language English
Publication Date Nov 2020
BACKGROUND: Refractory chronic cough (RCC) is a debilitating condition for which there are no licensed treatments. Lidocaine is a non-selective inhibitor of voltage gated sodium channels (VGSC) with potential anti-tussive effects, but randomized placebo-controlled studies evaluating its efficacy in RCC are lacking.