Authors Oakey, J.; Haslam, S.; Brown, A.; Eglin, J.; Houghton, B.; Singleton, D.
Source Annals of Clinical Biochemistry; Jun 2021; 58(5)
Abstract The aim of this study was to compare four high-throughput automated anti-SARS-CoV-2 assays using samples collected from hospitalized patients and healthcare workers with confirmed SARS-CoV-2 infection. All four assays showed excellent comparability, but it may be possible to obtain a negative result for any of the anti-SARS-CoV-2 assays in patients with confirmed previous SARS-CoV-2 infection. An equivocal range would be useful for all anti-SARS-CoV-2 assays. 

• Available in full text from SAGE Journals 

Author(s) Tebbutt J.E.; Markose G.; Graham R.M.
Source Annals of the Royal College of Surgeons of England; May 2021; vol. 103 (no. 5); p. 381-382

• Available at Annals of the Royal College of Surgeons of England from EBSCO (MEDLINE Complete)

Author(s) Sharrock M.; Whelton C.; Paton R.
Source British Journal of Surgery; May 2021; vol. 108
Introduction: Controversy exists surrounding the efficacy of the UK screening programme for developmental dysplasia of the hip (DDH). Method(s): Clinical records were reviewed in children who were treated surgically for DDH. Demographic data, age and mode of presentation, and surgical treatments were analysed, as well as outcomes, re-operation rate and AVN incidence. Late diagnosis was defined as greater than 4 months. 

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Author(s) Sharrock M.; Whelton C.; Paton R.
Source British Journal of Surgery; May 2021; vol. 108

Aim:: To assess the accuracy of clinical coding of developmental dysplasia of the hip (DDH) operations Method: 106 children underwent surgery for DDH at our turst from 1997 to 2018. Our coding department was sent a list of patients and operation dates and asked to tabulate data on what each operation had been coded as. We compared what each operation was coded as with the procedure actually performed (as per operation notes, clinic letters and intra-operative fluoroscopy images). 

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Author(s) Holmes B.; Mirza U.; Manning C.; Cooke R.; Jugdey R.
Source British Journal of Surgery; May 2021; vol. 108
Introduction: COVID-19 has placed unprecedented demand on services at ELHT and it has become necessary to have telephone clinics to reduce the number of face-to-face clinics. A 'telephone triage clinic' was set up for referrals from A&E. Our project evaluated patient and clinician satisfaction on this. 
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Author(s) Leiberman D.; Trivedy M.; Kausar A.
Source British Journal of Surgery; May 2021; vol. 108
Introduction: The 2020 ST3 recruitment year for Higher Surgical Training (HST) did not have a face-to-face interview due to COVID-19. Candidates were solely scored on portfolio self-assessment alone. We have assessed the impact on Core Surgical Trainee progression into ST3 by comparing the 2020 recruitment year with 2019. 

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Author(s) Ansari S.A.; Al-Jader B.; Khan N.; Younis F.
Source British Journal of Surgery; May 2021; vol. 108
Introduction: Higher number of cycling injuries were observed during the COVID-19 period in the United Kingdom at our institution. Many were serious injuries requiring hospitalisation and some requiring surgery. We investigated whether the lockdown led to a legitimate increase in incidence of cycling related injuries, resulting in a higher number of aerosol generating procedures (AGPs). This would assess whether the guidance on exercise during lockdown was appropriate, shaping future regulation in the case of cyclical lockdowns.

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Author(s) De Brito M.; Coulson I.H.; Dhawan G.; Alassaf J.; Bewley A.
Source British Journal of Dermatology; May 2021; vol. 184 (no. 5)
Pityriasis rubra pilaris (PRP) is a rare, papulosquamous dermatosis, which may progress to erythroderma. We present three cases of refractory type 1 PRP with complete response to ustekinumab, an anti-interleukin (IL)-12/IL-23 biologic. A 57-year-old woman presented with a pruritic psoriasiform eruption that responded incompletely to retinoid or methotrexate. It became widespread, with spared islands and palmoplantar keratoderma. Skin biopsy suggested type 1 PRP. Despite acitretin with ciclosporin, she developed erythroderma, which required hospital admission, and was refractory to azathioprine, systemic steroids and erythromycin. After her first injection of ustekinumab, her skin improved and she remains clear on ustekinumab. A 61-year-old man presented with a widespread scaling eruption diagnosed as type 1 PRP. Methotrexate was contraindicated owing to his alcohol intake. Acitretin was ineffective, with a significantly impaired quality of life [Dermatology Life Quality Index (DLQI) 16]. He became erythrodermic. After his first injection of ustekinumab, his erythema reduced by 50%. By the fourth injection, his skin was clear. He stopped ustekinumab after 18 months, and has remained clear since. A 64-year-old woman presented with type 1 PRP, with erythroderma, nail changes, orange keratoderma and spared islands over the trunk. She required admission and, despite acitretin, methotrexate, ciclosporin and infliximab, there was no improvement. Four weeks after her first ustekinumab injection, her skin was almost clear. Her DLQI reduced from 25 to 5. She stopped ustekinumab after 6 months and has remained clear since. Reports of ustekinumab in PRP are limited to case reports/case series, where 14/15 patients sustained a significant response at 4-8 weeks (Naidoo A, Sibbald C, Fleming et al. Use of biologics in pityriasis rubra pilaris refractory to first-line systemic therapy: a systematic review. J Cutan Med Surg 2020; 24: 77-8). These cases suggest that ustekinumab may be effective in refractory type 1 PRP.

• Available in full text at British Journal of Dermatology from Wiley Online Library Medicine and Nursing Collection 2013

Author(s) Sadozai Z.; Bokhari S.A.; Mannan K.
Source British Journal of Surgery; May 2021; vol. 108
Introduction: Effective communication skills are an extremely important aspect of good medical practice. Fractures are common with over 1 million fractures occurring each year in the UK; of which 5-10% may have problems with healing. Patient perceptions of factors harmful to the fracture healing process are unknown and our study investigates this. 

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Author(s) Elbayouk A.; Halim U.; Javed S.; Ali A.; Cullen C.
Source British Journal of Surgery; May 2021; vol. 108

Background: The aim of this systematic review was to outline the prevalence and impact of Gender bias and sexual discrimination (GBSD) in orthopaedics, and to investigate interventions countering such behaviours. 

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Author(s) Pramanik K.; Webb P.; Hamid R.
Source BMJ Case Reports; May 2021; vol. 14 (no. 5)
We present to you a case of life-threatening haemoptysis secondary to non-cystic fibrosis bronchiectasis complicated by bronchial artery pseudoaneurysms. We discuss this patient's emergency medical management using intravenous tranexamic acid, which resulted in successful resuscitation and eventual survival, and evaluate the need for urgent anaesthetic and interventional radiology input in such a case.Copyright ©

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Author(s) Chan V.W.-S.; Tan W.S.; Chiu P.K.-F.; Teoh J.Y.-C.; Leow J.J. et al.
Source World journal of urology; May 2021
PURPOSE: The COVID-19 pandemic has led to the cancellation or deferment of many elective cancer surgeries. We performed a systematic review on the oncological effects of delayed surgery for patients with localised or metastatic renal cell carcinoma (RCC) in the targeted therapy (TT) era. 

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Authors:Anna Kathryn Taylor; Steven Armitage; Ambareen Kausar
Source:  Health Expectations, Vol 24, Iss 4, Pp 1545-1546 (2021)
Language: English
Semi-structured interviews enable the exploration of a participant's views and experiences, and can reveal in-depth insights into a problem. Interviews usually consist of a dialogue between the researcher and the study participant.1 Dyadic interviewing2 is a form of qualitative research in which two participants interact and respond to open-ended questions posed by the researcher, recognizing and utilizing the interdependent relationship between individuals. This can be a useful approach for some research settings. Researchers may study the relationship between interviewees in addition to the data generated by their interaction, offering a joint perspective on shared problems such as management of chronic illness.3 The data from dyadic interviewing can be explored through considering the dyad as a single unit of analysis, or alternatively as two separate perspectives. Individual interviewing involves a single perspective but might enable that participant to speak more openly; there is a risk with dyadic interviewing that a disclosure from one interviewee could cause harm to the other, or one person may dominate the interview.3 Therefore, sensitive subjects may be better discussed in individual interviews. Sometimes, researchers encounter family members of study participants who wish to join a one-to-one interview; this may create a dilemma.

Available at Health Expectations from Wiley Online Library Medicine & Nursing Collection