Author(s) Wong ; Viyasar, Thevarajah; Layton, Benjamin; Lauder, Joshua
Source British Journal of Hospital Medicine (17508460); Nov 2022; vol. 82 (no. 11); p. 369-376 Language English Publication Date Nov 2022 DOI 10.12968/hmed.2021.0322 ISSN 17508460 Database CINAHL Nitrous oxide, also known as 'laughing gas', is one of the most widely used recreational drugs among teenagers in the UK. Copious inhalation of nitrous oxide may increase intra-alveolar pressure, resulting in barotrauma secondary to alveolar rupture. Pneumomediastinum and subcutaneous emphysema are common clinical findings in nitrous oxide-associated barotrauma. Prolonged nitrous oxide misuse may inactivate vitamin B12 through the alteration of its metabolism, causing demyelination of the central and peripheral nervous system. A spectrum of neurological manifestations has been reported, including peripheral neuropathy, myelopathy and subacute combined degeneration of the spinal cord. Medical therapies and psychosocial interventions aiming at nitrous oxide cessation are important treatment steps to achieve partial or complete recovery from the adverse effects associated with inhalation of nitrous oxide.
0 Comments
Author(s) Conti I.; Cross B.; Rooney A.G.; Nicholson T.R.
Source Journal of the Neurological Sciences; Jul 2021; vol. 426 Database EMBASE |
The following databases were searched:
EMBASE, MEDLINE, PsycINFO, BNI, CINAHL, to find ELHT staff publications Specialties
All
Archives
August 2022
|
Contact Us:
library@elht.nhs.uk Learning Centre Library Royal Blackburn Teaching Hospital 01254 734312 or Ext 84312 Find us |
Staffed Opening Hours
Mon 08:30-16:30 Tue 08:30-16:30 Wed 08:30-16:30 Thu 08:30-16:30 Fri 08:30-16:00 24/7 access to both libraries is available - please see library staff
|